Irritable bowel may be genetically linked to headachesStaff writer ▼ | February 26, 2016
Genetic links may exist between irritable bowel syndrome (IBS) and migraine and tension-type headaches, researchers report.
New research Two common conditions connected with genes
The findings might help point to new treatments for all of the disorders, suggested Uluduz, of Istanbul University in Turkey, and colleagues.
The study included 107 people with migraine, 53 with tension-type headache, 107 with IBS and 53 without any of the conditions.
People with migraine were about twice as likely as those with tension headache to also have IBS -- 54 percent versus 28 percent, respectively. Of the people with IBS, 38 also had migraine and 24 also had tension headache, the investigators found.
The researchers then focused on genetics, in particular, the serotonin transporter gene and the serotonin receptor 2A gene. The study authors found that people with IBS, migraine or tension headache had at least one gene that differed from those of people without any of the disorders.
The finding are scheduled for presentation in April at the American Academy of Neurology's annual meeting, in Vancouver, Canada. The data and conclusions should be considered preliminary until published in a peer-reviewed medical journal. ■