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Coronavirus vaccine trials not designed to detect risk reduction

Christian Fernsby ▼ | October 22, 2020
None of the trials of coronavirus candidate vaccines currently under way are designed to detect a reduction in serious outcomes such as hospitalisation or death, according to a leading public health expert.
Peter Doshi
Coronavirus vaccine   BMJ medical journal
Writing in the BMJ medical journal, associate editor Peter Doshi warned that not even the phase three trials under way in the race for a vaccine can prove their product will prevent people contracting coronavirus.

He said those hoping for a breakthrough to end the pandemic would be disappointed, with some vaccines likely to reduce the risk of Covid-1coronairus9 infection by only 30%.

"None of the trials currently under way are designed to detect a reduction in any serious outcome such as hospital admissions, use of intensive care, or deaths," he said.

"Nor are the vaccines being studied to determine whether they can interrupt transmission of the virus."


 

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